The Sperm Antibody Test (Total ASAB) is an important diagnostic tool used to detect anti-sperm antibodies—immune system proteins that mistakenly identify sperm as harmful invaders and interfere with their function. These antibodies can reduce the sperm’s ability to swim properly, reach the egg, or fertilize it, leading to difficulties in conception for both men and women. While not part of routine fertility testing, the Total ASAB test becomes crucial when couples face unexplained infertility, recurrent IVF failures, or have a history of infection, surgery, or trauma involving the reproductive organs. This simple, non-invasive test can be performed on a semen sample (in men), helping specialists uncover hidden immune-related causes of infertility. By identifying these antibodies, doctors can tailor treatment plans more effectively—whether through IUI, IVF, or other targeted therapies—bringing couples one step closer to their goal of parenthood. The Total ASAB test offers clarity when answers are hard to find, playing a key role in truly personalized fertility care