
Test Code -HT0586
This comprehensive test examines both the BRCA1 and BRCA2 genes for mutations and large deletions or duplications that may contribute to an increased risk of hereditary cancers. It is recommended for individuals with a strong family history of cancer or those meeting clinical criteria for genetic testing. The test provides critical insights for risk assessment, preventive strategies, and tailored treatment plans, helping individuals and healthcare providers make informed decisions about surveillance, lifestyle changes, and possible preventive interventions.
Description
BRCA1 and BRCA2 are two genes that have gained significant attention due to their connection with hereditary cancer, particularly breast and ovarian cancer. These genes, present in all humans, play a vital role in maintaining the integrity of our DNA by producing proteins that help repair damaged genetic material. When functioning properly, BRCA1 and BRCA2 act like a built-in repair system, fixing broken strands of DNA and preventing mutations that can lead to cancer. However, when a mutation occurs in either of these genes, their ability to repair DNA becomes impaired, which greatly increases the risk of developing certain cancers.These mutations also significantly raise the chances of ovarian cancer, and they aren’t limited to women. Men with BRCA2 mutations, in particular, are more likely to develop prostate cancer and even male breast cancer. The genetic link extends to other cancers as well, including pancreatic cancer and melanoma. While these mutations are not common in the general population, they are more prevalent in certain groups, such as individuals with a strong family history of cancer.Genetic testing for BRCA mutations is straightforward, typically involving a simple blood sample. It is often recommended for people with a personal or family history of cancers associated with BRCA mutations.Testing also aids in family planning and offers valuable insights that can be shared with family members who may also be at risk. BRCA1 and BRCA2 gene profile holds vital clues to a person’s cancer risk. While discovering a mutation can be overwhelming, it can also be life-saving. With the right information and support, individuals can take meaningful steps to protect their health and the health of future generations. Genetic awareness doesn’t determine your fate—but it does give you the power to shape your future with confidence and clarity.
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