The tTG Antibody IgG Test (Tissue Transglutaminase IgG) is a powerful diagnostic tool designed to detect Celiac disease, an autoimmune disorder triggered by the ingestion of gluten—a protein found in wheat, barley, and rye.When someone with Celiac disease consumes gluten, their immune system responds by producing antibodies that attack the body’s own tissue, particularly the small intestine. This immune reaction can lead to chronic inflammation and damage to the intestinal lining, impairing the body’s ability to absorb essential nutrients. Over time, it can cause a range of symptoms including bloating, fatigue, digestive discomfort, weight loss, skin rashes, and nutrient deficiencies—and sometimes, no symptoms at all.The tTG IgG test detects the presence of anti-tissue transglutaminase antibodies, which are elevated in individuals whose immune systems are reacting to gluten. This simple blood test helps uncover the underlying cause of unexplained gastrointestinal symptoms and long-standing health issues that may have gone undiagnosed. Early detection of Celiac disease is critical—not only to relieve symptoms but also to prevent long-term complications such as malnutrition, osteoporosis, infertility, neurological disorders, and more.Whether you’re experiencing symptoms or have a faTaking the test is straightforward, and results are interpreted alongside other clinical information to help your healthcare provider make an accurate diagnosis. If positive, a gluten-free lifestyle can dramatically improve your quality of life and restore your digestive health.mily history of Celiac disease, the tTG Antibody IgG Test provides clear, actionable insight into your body’s immune response to gluten. It’s also helpful for monitoring response to a gluten-free diet and assessing ongoing inflammation.